/* Karyotype Workbench specific styles (inherits from style.css) */

/* ── Theme Toggle: Textbook (light) vs Microscope (dark) ─────────── */
body.karyo-light {
  --bg: #f8fafc;
  --bg-card: #ffffff;
  --bg-hover: #f1f5f9;
  --text: #0f172a;
  --text-muted: #475569;
  --text-dim: #94a3b8;
  --border: #cbd5e1;
}

/* G-banding palette inverts based on theme */
.band-gneg     { fill: #1e293b; }
.band-gpos25   { fill: #475569; }
.band-gpos50   { fill: #6b7280; }
.band-gpos75   { fill: #9ca3af; }
.band-gpos100  { fill: #e5e7eb; }
body.karyo-light .band-gneg     { fill: #f8fafc; }
body.karyo-light .band-gpos25   { fill: #cbd5e1; }
body.karyo-light .band-gpos50   { fill: #94a3b8; }
body.karyo-light .band-gpos75   { fill: #475569; }
body.karyo-light .band-gpos100  { fill: #1e293b; }

/* Real specimen photos: dark = mikroskop (no invert), light = textbook (invert) */
body.karyo-light .pager-img,
body.karyo-light .pager-img-wrap {
  background: #fff;
}
body.karyo-light .pager-img {
  filter: invert(1) brightness(0.95) contrast(1.1);
}
body.karyo-light .pager {
  background: #f1f5f9;
}
body.karyo-light .schema-pager-host {
  background: #fff;
  border: 1px solid var(--border);
}

.lang-toggle {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--accent);
  width: 28px;
  height: 24px;
  border-radius: 5px;
  font-size: 0.6rem;
  font-weight: 700;
  cursor: pointer;
  font-family: inherit;
  transition: all 0.12s;
  display: flex;
  align-items: center;
  justify-content: center;
  padding: 0;
}
.lang-toggle:hover { border-color: var(--accent); }

.theme-toggle {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text-muted);
  width: 28px;
  height: 24px;
  border-radius: 5px;
  font-size: 0.85rem;
  cursor: pointer;
  font-family: inherit;
  transition: all 0.12s;
  display: flex;
  align-items: center;
  justify-content: center;
  padding: 0;
}
.theme-toggle:hover { border-color: var(--accent-dim); color: var(--accent); }
.mode-bar { justify-content: space-between; }

/* Mode bar */
.mode-bar {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 0.4rem 0.8rem;
  border-bottom: 1px solid var(--border);
  gap: 0.5rem;
  flex-wrap: wrap;
}
.mode-tabs { display: flex; gap: 2px; flex-wrap: wrap; }
.mode-tab {
  background: none;
  border: 1px solid var(--border);
  color: var(--text-dim);
  padding: 0.25rem 0.6rem;
  border-radius: 5px;
  cursor: pointer;
  font-size: 0.72rem;
  font-family: inherit;
  transition: all 0.12s;
}
.mode-tab:hover { color: var(--text-muted); border-color: var(--accent-dim); }
.mode-tab.active { background: var(--accent-dim); border-color: var(--accent); color: #fff; }

/* Mode panels */
.mode-panel { display: none; }
.mode-panel.active { display: block; }

/* ── Karyogram (24 chromosomes, Denver A-G groups) ───────────────── */
.karyogram {
  padding: 0.6rem 0.8rem;
}
.kgroup {
  margin-bottom: 0.7rem;
}
.kgroup-label {
  font-size: 0.6rem;
  color: var(--text-dim);
  text-transform: uppercase;
  letter-spacing: 0.5px;
  margin-bottom: 0.2rem;
  font-weight: 600;
}
.kgroup-row {
  display: flex;
  gap: 6px;
  align-items: flex-end;
  flex-wrap: wrap;
}
.chr-pair {
  display: flex;
  flex-direction: column;
  align-items: center;
  cursor: pointer;
  transition: opacity 0.12s;
}
.chr-pair:hover { opacity: 0.85; }
.chr-pair.selected .chr-svg { filter: drop-shadow(0 0 2px var(--accent)); }
.chr-pair-svgs { display: flex; gap: 1px; align-items: flex-end; }
.chr-svg { display: block; }
.chr-num {
  font-size: 0.55rem;
  color: var(--text-dim);
  margin-top: 0.15rem;
  font-family: monospace;
}

/* Chromosome bands - acen, gvar, stalk are constant; gneg/gpos handled by theme */
.band-acen     { fill: var(--accent); }
.band-gvar     { fill: #818cf8; }
.band-stalk    { fill: #f59e0b; }

/* Chromosome outline */
.chr-outline {
  fill: none;
  stroke: var(--border);
  stroke-width: 0.5;
}

/* ── Build Game (sort chromosomes into slots) ────────────────────── */
.build-toolbar {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 0.4rem 0.8rem;
  border-bottom: 1px solid var(--border);
  gap: 0.4rem;
  flex-wrap: wrap;
}
.build-status {
  font-size: 0.72rem;
  color: var(--text-muted);
  font-family: monospace;
}
.build-buttons { display: flex; gap: 4px; flex-wrap: wrap; }
.build-diff-btn,
.build-action-btn {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text-muted);
  padding: 0.25rem 0.55rem;
  border-radius: 4px;
  font-size: 0.65rem;
  cursor: pointer;
  font-family: inherit;
}
.build-diff-btn:hover,
.build-action-btn:hover { border-color: var(--accent-dim); color: var(--text); }
.build-diff-btn.active { background: var(--accent-dim); border-color: var(--accent); color: #fff; }
.build-action-btn { background: var(--accent-dim); color: #fff; border-color: var(--accent); font-weight: 600; }
.build-action-btn:disabled { opacity: 0.4; cursor: not-allowed; }
.build-action-btn.secondary { background: var(--bg); color: var(--text-muted); font-weight: 400; border-color: var(--border); }

.build-spread {
  display: flex;
  flex-wrap: wrap;
  gap: 4px;
  padding: 0.5rem;
  background: #000;
  border-radius: 6px;
  margin: 0.5rem 0.8rem;
  min-height: 90px;
  max-height: 200px;
  overflow-y: auto;
  align-content: flex-start;
}
body.karyo-light .build-spread { background: #f1f5f9; }

.build-piece {
  width: 50px;
  height: 80px;
  display: flex;
  align-items: center;
  justify-content: center;
  cursor: pointer;
  border: 2px solid transparent;
  border-radius: 4px;
  transition: all 0.12s;
  flex-shrink: 0;
  background: rgba(255,255,255,0.02);
}
.build-piece:hover {
  border-color: var(--accent-dim);
  background: rgba(6,182,212,0.1);
}
.build-piece.selected {
  border-color: var(--accent);
  background: rgba(6,182,212,0.2);
  box-shadow: 0 0 8px rgba(6,182,212,0.5);
}
.build-piece img {
  max-width: 100%;
  max-height: 100%;
  display: block;
  pointer-events: none;
  transition: none;
}

.build-grid {
  padding: 0.5rem 0.8rem;
}
.build-group {
  margin-bottom: 0.5rem;
}
.build-group-label {
  font-size: 0.55rem;
  color: var(--text-dim);
  text-transform: uppercase;
  letter-spacing: 0.5px;
  font-weight: 600;
  margin-bottom: 0.2rem;
}
.build-group-row {
  display: flex;
  gap: 4px;
  flex-wrap: wrap;
  align-items: flex-end;
}
.build-slot-pair {
  display: flex;
  flex-direction: column;
  align-items: center;
}
.build-slot-pair > div:not(:last-child) { display: flex; }
.build-slot-pair .build-slot + .build-slot { margin-top: 2px; }
.build-slot {
  width: 38px;
  height: 60px;
  border: 1px dashed var(--border);
  border-radius: 4px;
  display: flex;
  align-items: center;
  justify-content: center;
  background: var(--bg);
  cursor: pointer;
  transition: all 0.12s;
  padding: 2px;
}
.build-slot:hover { border-color: var(--accent-dim); background: var(--bg-hover); }
.build-slot.correct {
  border: 2px solid var(--success);
  background: rgba(16,185,129,0.1);
}
.build-slot.incorrect {
  border: 2px solid var(--danger);
  background: rgba(239,68,68,0.1);
}
.build-slot .build-piece {
  width: 100%;
  height: 100%;
  border: none;
  background: transparent;
  cursor: pointer;
}
.build-slot-label {
  font-size: 0.55rem;
  color: var(--text-dim);
  font-family: monospace;
  margin-top: 2px;
}

.build-hint {
  font-size: 0.6rem;
  color: var(--text-dim);
  padding: 0.4rem 0.8rem;
  line-height: 1.4;
  border-top: 1px solid var(--border);
  background: var(--bg);
}

/* ── Build single mode ───────────────────────────────────────────── */
.build-view-btn {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text-muted);
  padding: 0.2rem 0.5rem;
  border-radius: 4px;
  font-size: 0.65rem;
  cursor: pointer;
  font-family: inherit;
}
.build-view-btn:hover { border-color: var(--accent-dim); }
.build-view-btn.active { background: var(--accent-dim); color: #fff; border-color: var(--accent); }

.build-single {
  display: flex;
  flex-direction: column;
  align-items: center;
  padding: 0.6rem 0.8rem;
  gap: 0.5rem;
}
.build-single.correct { background: rgba(16,185,129,0.08); }
.build-single.incorrect { background: rgba(239,68,68,0.08); }
.build-single-counter {
  font-size: 0.7rem;
  color: var(--text-dim);
  font-family: monospace;
}
.build-single-img-wrap {
  background: #000;
  border-radius: 8px;
  width: 200px;
  height: 260px;
  display: flex;
  align-items: center;
  justify-content: center;
  overflow: hidden;
  cursor: grab;
}
body.karyo-light .build-single-img-wrap { background: #f1f5f9; }
.build-single-img-wrap img {
  max-width: 90%;
  max-height: 240px;
  pointer-events: none;
  transition: transform 0.1s;
}
.build-single-controls {
  display: flex;
  gap: 4px;
  align-items: center;
}
.build-rotation-display {
  font-family: monospace;
  color: var(--accent-dim);
  font-size: 0.65rem;
  min-width: 35px;
  text-align: center;
}
.build-assign-select {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text);
  padding: 0.4rem 0.6rem;
  border-radius: 5px;
  font-size: 0.8rem;
  font-family: inherit;
  width: 200px;
  text-align: center;
}
.build-correct-answer {
  color: var(--success);
  font-size: 0.75rem;
  font-weight: 600;
  font-family: monospace;
}
.build-single-nav {
  display: flex;
  gap: 0.5rem;
  align-items: center;
}
.build-single-nav-bottom {
  display: flex;
  justify-content: center;
  padding: 0.4rem 0.8rem;
  border-top: 1px solid var(--border);
}

/* Build single layout: image + optional hint side */
.build-single-layout {
  display: flex;
  gap: 0.5rem;
  padding: 0 0.8rem;
  align-items: flex-start;
  justify-content: center;
}

/* Hint side panel (next to real image) */
.build-hint-side {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 6px;
  padding: 0.4rem;
  max-height: 380px;
  overflow-y: auto;
  flex-shrink: 0;
  width: 240px;
}
.build-hint-label {
  font-size: 0.58rem;
  color: var(--warning);
  text-transform: uppercase;
  letter-spacing: 0.5px;
  margin-bottom: 0.3rem;
  font-weight: 600;
  text-align: center;
}
.build-hint-all {
  display: grid;
  grid-template-columns: repeat(6, 1fr);
  gap: 2px;
}
.build-hint-chr {
  display: flex;
  flex-direction: column;
  align-items: center;
  cursor: default;
  padding: 1px;
  border-radius: 3px;
  transition: background 0.1s;
}
.build-hint-chr:hover { background: var(--bg-hover); }
.build-hint-svg svg { display: block; }
.build-hint-num {
  font-size: 0.5rem;
  color: var(--text-dim);
  font-family: monospace;
}

/* Flash feedback after answer */
.build-flash {
  text-align: center;
  font-size: 0.85rem;
  font-weight: 700;
  padding: 0.4rem;
  border-radius: 5px;
  margin: 0.3rem 0;
  animation: flash-fade 0.6s ease-out;
}
.flash-correct { color: var(--success); background: rgba(16,185,129,0.15); }
.flash-wrong { color: var(--danger); background: rgba(239,68,68,0.15); }
@keyframes flash-fade {
  0% { opacity: 0; transform: scale(0.9); }
  30% { opacity: 1; transform: scale(1.05); }
  100% { opacity: 1; transform: scale(1); }
}

@media (max-width: 480px) {
  .build-single-layout { flex-direction: column; align-items: center; }
  .build-hint-side { width: 100%; max-height: 200px; }
}
.build-area {
  padding: 0.6rem 0.8rem;
}
.metaphase-spread {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 6px;
  padding: 0.6rem;
  min-height: 180px;
  position: relative;
  margin-bottom: 0.6rem;
}
.spread-chr {
  position: absolute;
  cursor: grab;
  transition: filter 0.12s;
}
.spread-chr:hover { filter: drop-shadow(0 0 3px var(--accent)); }
.spread-chr.dragging { cursor: grabbing; opacity: 0.5; }
.spread-chr.placed { display: none; }

.build-slots {
  display: flex;
  flex-wrap: wrap;
  gap: 4px;
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 6px;
  padding: 0.5rem;
  min-height: 120px;
}
.slot {
  border: 1px dashed var(--border);
  border-radius: 4px;
  min-width: 30px;
  min-height: 60px;
  display: flex;
  flex-direction: column;
  align-items: center;
  padding: 2px;
}
.slot.drop-target { border-color: var(--accent); background: rgba(6,182,212,0.08); }
.slot.correct { border-color: var(--success); border-style: solid; }
.slot.incorrect { border-color: var(--danger); border-style: solid; }
.slot-label {
  font-size: 0.55rem;
  color: var(--text-dim);
  font-family: monospace;
  margin-top: 2px;
}

.build-controls {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 0.4rem 0.8rem;
  border-top: 1px solid var(--border);
  gap: 0.5rem;
}
.build-stats { font-size: 0.72rem; color: var(--text-muted); font-family: monospace; }
.build-btn {
  background: var(--accent-dim);
  color: #fff;
  border: none;
  padding: 0.3rem 0.7rem;
  border-radius: 5px;
  font-size: 0.72rem;
  cursor: pointer;
  font-family: inherit;
  font-weight: 600;
}
.build-btn:hover { background: var(--accent); }
.build-btn.secondary { background: var(--bg); border: 1px solid var(--border); color: var(--text-muted); }

/* ── Compare Mode (schema left, real-pager right) ─────────────────── */
.compare-split {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 0.5rem;
  padding: 0.6rem 0.8rem;
}
.compare-side {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 6px;
  padding: 0.5rem;
  min-height: 380px;
  display: flex;
  flex-direction: column;
}
.compare-side h3 {
  font-size: 0.7rem;
  color: var(--text-muted);
  margin-bottom: 0.4rem;
  text-align: center;
  font-weight: 600;
  text-transform: uppercase;
  letter-spacing: 0.5px;
}

/* Schema side: large chromosome on top, mini-grid below */
.schema-pager-host {
  background: #000;
  border-radius: 6px;
  padding: 0.5rem;
  margin-bottom: 0.4rem;
  display: flex;
  flex-direction: column;
  align-items: center;
  min-height: 340px;
  flex: 1;
}
.schema-pager-host #schema-large {
  display: flex;
  align-items: center;
  justify-content: center;
  flex: 1;
}
.schema-pager-host #schema-large svg { display: block; }
.schema-pager-host #schema-large rect[data-band] {
  cursor: crosshair;
  transition: filter 0.1s;
}
.schema-pager-host #schema-large rect[data-band]:hover {
  filter: brightness(1.5) drop-shadow(0 0 2px var(--accent));
}
.schema-large-label {
  font-size: 0.65rem;
  color: var(--text-dim);
  font-family: monospace;
  margin-top: 0.4rem;
  text-align: center;
}
.schema-mini-grid {
  background: var(--bg-card);
  border-radius: 5px;
  padding: 0.3rem;
  max-height: 130px;
  overflow-y: auto;
}
.schema-mini-grid .kgroup {
  margin-bottom: 0.3rem;
}
.schema-mini-grid .kgroup-label {
  font-size: 0.5rem;
}
.schema-mini-grid .chr-pair { transition: filter 0.12s; }
.schema-mini-grid .chr-pair:hover { filter: drop-shadow(0 0 3px var(--accent)) brightness(1.2); }
.schema-mini-grid .chr-pair.selected { filter: drop-shadow(0 0 5px var(--accent)) brightness(1.4); }
.schema-mini-grid .chr-pair.selected .chr-num { color: var(--accent); font-weight: 700; }

/* Pager (right side, single-chromosome browser) */
.pager {
  flex: 1;
  display: flex;
  flex-direction: column;
  align-items: center;
  gap: 0.3rem;
  background: #000;
  border-radius: 6px;
  padding: 0.5rem;
}
.pager-main {
  display: flex;
  align-items: center;
  gap: 0.4rem;
  flex: 1;
  width: 100%;
  justify-content: center;
}
.pager-img-wrap {
  flex: 1;
  display: flex;
  align-items: center;
  justify-content: center;
  background: #000;
  min-height: 240px;
  max-height: 320px;
  overflow: hidden;
  cursor: grab;
  user-select: none;
  -webkit-user-select: none;
  position: relative;
  touch-action: none;
}
.pager-img-wrap.rotating { cursor: grabbing; }
.pager-img-wrap::before {
  content: "\2935 drag to rotate";
  position: absolute;
  bottom: 4px;
  left: 50%;
  transform: translateX(-50%);
  font-size: 0.55rem;
  color: var(--text-dim);
  opacity: 0.5;
  pointer-events: none;
  font-family: monospace;
}
.pager-img {
  max-width: 80%;
  max-height: 280px;
  height: auto;
  display: block;
  border-radius: 3px;
  transition: transform 0.05s linear;
  pointer-events: none;
}

.pager-controls {
  display: flex;
  justify-content: center;
  margin-top: 0.3rem;
}
.pager-mini-btn {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text-muted);
  padding: 0.2rem 0.5rem;
  border-radius: 4px;
  font-size: 0.62rem;
  cursor: pointer;
  font-family: inherit;
}
.pager-mini-btn:hover { border-color: var(--accent-dim); color: var(--accent); }

#pager-rotation {
  font-family: monospace;
  color: var(--accent-dim);
  font-size: 0.7rem;
}
.pager-arrow {
  background: var(--bg-card);
  border: 1px solid var(--border);
  color: var(--text-muted);
  border-radius: 5px;
  padding: 0.3rem 0.6rem;
  cursor: pointer;
  font-size: 0.85rem;
  font-family: inherit;
  transition: all 0.12s;
  line-height: 1;
}
.pager-arrow:hover { background: var(--accent-dim); border-color: var(--accent); color: #fff; }
.pager-arrow:active { transform: scale(0.95); }
.pager-arrow.pager-up,
.pager-arrow.pager-down { width: 100%; padding: 0.25rem 0; }
.pager-arrow.pager-left,
.pager-arrow.pager-right { padding: 0.5rem 0.4rem; }

.pager-meta {
  display: flex;
  justify-content: space-between;
  width: 100%;
  margin-top: 0.4rem;
  font-size: 0.72rem;
  color: var(--text-muted);
  font-family: monospace;
}
.pager-meta #pager-chr-label { color: var(--accent); font-weight: 600; }
.pager-license {
  font-size: 0.55rem;
  color: var(--text-dim);
  margin-top: 0.3rem;
  text-align: center;
}

.compare-info {
  padding: 0.4rem 0.8rem;
  background: var(--bg);
  border-top: 1px solid var(--border);
  font-size: 0.7rem;
  color: var(--text-muted);
  min-height: 2.4em;
  line-height: 1.4;
}
.compare-info .info-band { color: var(--accent); font-weight: 600; font-family: monospace; }
.compare-info .info-genes { color: var(--text-dim); font-size: 0.65rem; }

@media (max-width: 480px) {
  .compare-split { grid-template-columns: 1fr; }
}

/* ── Aberrations Mode ────────────────────────────────────────────── */
.aberration-presets {
  padding: 0.5rem 0.8rem;
  border-bottom: 1px solid var(--border);
}
.aberration-categories {
  display: flex;
  gap: 4px;
  overflow-x: auto;
  margin-bottom: 0.4rem;
}
.cat-btn {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text-muted);
  padding: 0.2rem 0.5rem;
  border-radius: 4px;
  font-size: 0.68rem;
  cursor: pointer;
  font-family: inherit;
  white-space: nowrap;
}
.cat-btn:hover { border-color: var(--accent-dim); color: var(--text); }
.cat-btn.active { background: var(--accent-dim); border-color: var(--accent); color: #fff; }

.preset-grid {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 4px;
}
.preset-syndrome {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 5px;
  padding: 0.35rem 0.5rem;
  cursor: pointer;
  text-align: left;
  font-family: inherit;
  color: var(--text);
  transition: all 0.12s;
}
.preset-syndrome:hover { border-color: var(--accent-dim); background: var(--bg-hover); }
.preset-syndrome.active { border-color: var(--accent); background: var(--bg-hover); }
.preset-syndrome .ps-name { font-size: 0.72rem; font-weight: 600; }
.preset-syndrome .ps-iscn { font-size: 0.62rem; color: var(--text-dim); font-family: monospace; margin-top: 0.1rem; }
.preset-syndrome .ps-freq { font-size: 0.6rem; color: var(--accent-dim); margin-top: 0.1rem; }

.aberration-info {
  padding: 0.5rem 0.8rem;
  border-top: 1px solid var(--border);
  font-size: 0.75rem;
  line-height: 1.45;
}
.aberration-info h3 {
  font-size: 0.85rem;
  color: var(--accent);
  margin-bottom: 0.3rem;
  font-weight: 700;
}
.aberration-info .features {
  color: var(--text-muted);
  margin-top: 0.3rem;
}
.aberration-info .clingen-badge {
  display: inline-block;
  background: var(--accent-dim);
  color: #fff;
  padding: 0.1rem 0.4rem;
  border-radius: 3px;
  font-size: 0.6rem;
  font-weight: 600;
  text-transform: uppercase;
  margin-left: 0.4rem;
}
.aberration-info .iscn-line {
  font-family: monospace;
  color: var(--accent);
  font-size: 0.78rem;
  margin: 0.2rem 0;
}

/* Aberration markers on chromosomes */
.aberration-marker { stroke-width: 2; fill: none; }
.aberration-marker.deletion { stroke: var(--danger); }
.aberration-marker.duplication { stroke: var(--success); }
.aberration-marker.translocation { stroke: var(--warning); }
.aberration-marker.inversion { stroke: #818cf8; }

/* Highlighted band (deletion target) */
.aberration-highlighted {
  stroke: var(--danger);
  stroke-width: 1.5;
  filter: drop-shadow(0 0 4px var(--danger));
  animation: pulse-aberration 2s ease-in-out infinite;
}
@keyframes pulse-aberration {
  0%, 100% { stroke-opacity: 1; }
  50% { stroke-opacity: 0.4; }
}

/* Aberration zoom view (deletion) */
.aberration-zoom-view {
  display: flex;
  gap: 0.8rem;
  align-items: flex-start;
  padding: 0.5rem 0;
}
.aberration-zoom-svg {
  flex-shrink: 0;
}
.chr-svg-large rect[data-band] {
  cursor: crosshair;
}
.chr-svg-large .band-label {
  font-size: 4px;
  fill: var(--text-dim);
  font-family: monospace;
}
body.karyo-light .chr-svg-large .band-label {
  fill: var(--text-muted);
}
.aberration-zoom-info {
  flex: 1;
  font-size: 0.72rem;
  color: var(--text-muted);
  line-height: 1.5;
}
.azi-label {
  font-size: 0.6rem;
  text-transform: uppercase;
  letter-spacing: 0.5px;
  color: var(--text-dim);
}
.azi-region {
  font-family: monospace;
  color: var(--accent);
  font-size: 1.1rem;
  font-weight: 700;
  margin: 0.2rem 0 0.4rem;
}
.azi-note {
  background: var(--bg);
  border-left: 3px solid var(--warning);
  padding: 0.4rem 0.6rem;
  border-radius: 4px;
  font-size: 0.7rem;
}
.azi-tooltip {
  margin-top: 0.4rem;
  font-family: monospace;
  color: var(--accent);
  font-size: 0.75rem;
  min-height: 1em;
}

/* Translocation view */
.translocation-view {
  display: flex;
  align-items: center;
  justify-content: center;
  gap: 1rem;
  padding: 0.8rem 0.5rem;
}
.trans-pair {
  display: flex;
  flex-direction: column;
  align-items: center;
}
.trans-label {
  font-size: 0.65rem;
  color: var(--text-dim);
  font-family: monospace;
  margin-bottom: 0.3rem;
}
.trans-svg svg { display: block; }
.trans-arrow {
  font-size: 1.5rem;
  color: var(--accent);
  font-weight: 700;
}
.trans-explainer {
  padding: 0.5rem 0.8rem;
  background: var(--bg);
  border-left: 3px solid var(--accent-dim);
  border-radius: 4px;
  font-size: 0.7rem;
  color: var(--text-muted);
  line-height: 1.5;
  margin: 0 0.8rem 0.5rem;
}
.trans-explainer strong { color: var(--accent); }

/* Robertson segregation animation */
.segregation-area {
  padding: 0.5rem 0.8rem;
  border-top: 1px solid var(--border);
}
.segregation-title {
  font-size: 0.72rem;
  color: var(--text-muted);
  margin-bottom: 0.4rem;
  font-weight: 600;
}
.gametes-row {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  gap: 4px;
  margin-bottom: 0.4rem;
}
.gamete {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 4px;
  padding: 0.3rem;
  text-align: center;
  font-size: 0.65rem;
}
.gamete .g-label { color: var(--text-dim); font-size: 0.58rem; }
.gamete .g-result { font-weight: 600; margin-top: 0.15rem; }
.gamete.normal { border-color: var(--success); }
.gamete.balanced { border-color: var(--accent); }
.gamete.trisomy { border-color: var(--danger); }
.gamete.monosomy { border-color: var(--warning); }
.gamete .g-pheno { font-size: 0.55rem; color: var(--text-dim); margin-top: 0.15rem; }

/* ── Quiz / Exam Mode ────────────────────────────────────────────── */
.qz-header {
  display: flex;
  align-items: center;
  padding: 0.4rem 0.8rem;
  border-bottom: 1px solid var(--border);
  font-size: 0.7rem;
  color: var(--text-muted);
  gap: 0.5rem;
}
.qz-sub-tabs {
  display: flex;
  gap: 2px;
  padding: 0.3rem 0.8rem;
  border-bottom: 1px solid var(--border);
  overflow-x: auto;
}
.qz-sub-tab {
  background: none;
  border: 1px solid var(--border);
  color: var(--text-dim);
  padding: 0.2rem 0.5rem;
  border-radius: 4px;
  font-size: 0.65rem;
  cursor: pointer;
  font-family: inherit;
  white-space: nowrap;
}
.qz-sub-tab:hover { border-color: var(--accent-dim); color: var(--text); }
.qz-sub-tab.active { background: var(--accent-dim); border-color: var(--accent); color: #fff; }
.qz-sub-tab.done { border-color: var(--success); color: var(--success); }

.qz-karyo {
  background: #000;
  border-radius: 6px;
  padding: 0.5rem;
  margin-bottom: 0.4rem;
  text-align: center;
  min-height: 80px;
  display: flex;
  align-items: center;
  justify-content: center;
}
body.karyo-light .qz-karyo { background: #f1f5f9; }
.qz-karyo-img {
  max-width: 100%;
  max-height: 200px;
  display: block;
  margin: 0 auto;
  filter: invert(1) brightness(0.92);
}
body.karyo-light .qz-karyo-img { filter: none; }
.qz-iscn-display {
  font-family: monospace;
  color: var(--accent);
  font-size: 1rem;
  font-weight: 700;
  padding: 1rem;
}
.qz-iscn-line {
  font-family: monospace;
  color: var(--accent-dim);
  font-size: 0.72rem;
  text-align: center;
  margin-bottom: 0.4rem;
}
.qz-explain {
  display: none;
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 5px;
  padding: 0.5rem 0.7rem;
  font-size: 0.72rem;
  line-height: 1.5;
  margin-top: 0.4rem;
  color: var(--text-muted);
}
.qz-explain.show { display: block; }
.qz-explain strong { color: var(--success); }

.qz-diff-toggle { display: flex; gap: 2px; margin-left: auto; }
.qz-diff-btn {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text-dim);
  padding: 0.15rem 0.4rem;
  border-radius: 3px;
  font-size: 0.6rem;
  cursor: pointer;
  font-family: inherit;
}
.qz-diff-btn:hover { border-color: var(--accent-dim); color: var(--text); }
.qz-diff-btn.active { background: var(--accent-dim); color: #fff; border-color: var(--accent); }
.qz-diff-btn:disabled { opacity: 0.3; cursor: not-allowed; }
.qz-diff-btn[data-diff="facharzt"].active { background: var(--danger); border-color: var(--danger); }

/* ── Legacy Quiz Mode (kept for compat) ──────────────────────────── */
.quiz-area {
  padding: 0.6rem 0.8rem;
}
.quiz-question {
  font-size: 0.85rem;
  margin-bottom: 0.5rem;
  color: var(--text);
}
.quiz-karyo {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 6px;
  padding: 0.5rem;
  margin-bottom: 0.5rem;
  min-height: 100px;
}
.quiz-choices {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 4px;
  margin-bottom: 0.4rem;
}
.quiz-choice {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text);
  padding: 0.4rem 0.6rem;
  border-radius: 5px;
  cursor: pointer;
  font-family: inherit;
  font-size: 0.75rem;
  text-align: left;
  transition: all 0.12s;
}
.quiz-choice:hover { border-color: var(--accent-dim); }
.quiz-choice.correct { border-color: var(--success); background: rgba(16,185,129,0.1); }
.quiz-choice.wrong { border-color: var(--danger); background: rgba(239,68,68,0.1); }
.quiz-feedback {
  padding: 0.4rem 0.6rem;
  border-radius: 5px;
  font-size: 0.72rem;
  margin-top: 0.4rem;
  display: none;
}
.quiz-feedback.show { display: block; }
.quiz-feedback.correct { background: rgba(16,185,129,0.1); border: 1px solid var(--success); }
.quiz-feedback.wrong { background: rgba(239,68,68,0.1); border: 1px solid var(--danger); }
.quiz-stats {
  display: flex;
  justify-content: space-between;
  font-size: 0.7rem;
  color: var(--text-dim);
  margin-bottom: 0.4rem;
  font-family: monospace;
}

/* ── Exam Mode (50 cases) ────────────────────────────────────────── */
.exam-header {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 0.4rem 0.8rem;
  border-bottom: 1px solid var(--border);
  font-size: 0.7rem;
  color: var(--text-muted);
}
.exam-progress-bar {
  height: 4px;
  background: var(--bg);
  border-radius: 2px;
  overflow: hidden;
  margin: 0 0.5rem;
  flex: 1;
}
.exam-progress-fill {
  height: 100%;
  background: var(--accent);
  transition: width 0.3s;
}
.exam-counter { font-family: monospace; font-size: 0.7rem; }

.exam-case {
  padding: 0.6rem 0.8rem;
}
.exam-vignette {
  background: var(--bg);
  border-left: 3px solid var(--accent-dim);
  padding: 0.5rem 0.7rem;
  border-radius: 4px;
  font-size: 0.75rem;
  color: var(--text-muted);
  margin-bottom: 0.5rem;
  line-height: 1.45;
}
.exam-vignette strong { color: var(--text); }
.exam-karyo {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 6px;
  padding: 0.5rem;
  margin-bottom: 0.5rem;
  min-height: 100px;
}
.exam-explanation {
  background: var(--bg);
  border: 1px solid var(--border);
  border-radius: 5px;
  padding: 0.5rem 0.7rem;
  font-size: 0.72rem;
  line-height: 1.5;
  margin-top: 0.4rem;
  display: none;
  color: var(--text-muted);
}
.exam-explanation.show { display: block; }
.exam-explanation .iscn { font-family: monospace; color: var(--accent); }
.exam-explanation .key { color: var(--text); font-weight: 600; }

.exam-controls {
  display: flex;
  justify-content: space-between;
  padding: 0.4rem 0.8rem;
  border-top: 1px solid var(--border);
  gap: 0.5rem;
}
.exam-controls button {
  background: var(--bg);
  border: 1px solid var(--border);
  color: var(--text-muted);
  padding: 0.3rem 0.7rem;
  border-radius: 5px;
  font-size: 0.7rem;
  cursor: pointer;
  font-family: inherit;
}
.exam-controls button:hover { border-color: var(--accent-dim); color: var(--text); }
.exam-controls button.primary { background: var(--accent-dim); color: #fff; border-color: var(--accent); }

.exam-stats-grid {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 4px;
  padding: 0.4rem 0.8rem;
  border-top: 1px solid var(--border);
}
.exam-cat {
  background: var(--bg);
  border-radius: 4px;
  padding: 0.3rem 0.5rem;
  font-size: 0.65rem;
}
.exam-cat-name { color: var(--text-muted); }
.exam-cat-score { color: var(--accent); font-family: monospace; float: right; }