Helix
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Interactive Human Genetics — real data, real science
p²+2pq+q²
Hardy-Weinberg
Allele frequencies, HWE testing, gnomAD data
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Aa×Aa
Mendel Lab
Crosses, pedigrees, inheritance patterns
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Evolution Sandbox
Drift, selection, migration, bottleneck — WASM-powered
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ΔDNA
Mutations
Point mutations, frameshifts, protein effects
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Tumor Genetics
Multi-hit model, Knudson, COSMIC data
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Karyotype
Cytogenetics, aberrations, 50-case exam mode
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Hardy-Weinberg Explorer
Allele frequency (p)
0.500
Inbreeding (F)
0.000
Compare with real variants
(click to load gnomAD data)
HBB rs334
Sickle Cell
MTHFR C677T
Factor V Leiden
CFTR F508del
BRCA1 5382insC
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Population labels (AFR, EUR, etc.) refer to geographic sampling regions in gnomAD, not to biological categories. Human genetic variation is continuous, not categorical.
ASHG 2018